University of MissouriUniversity of Missouri
Jianlin Cheng

Jianlin Cheng

Assistant Professor
Department of Computer Science

E-mail: chengji@missouri.edu
Web site: Cheng Lab
Office address: Engineering Building West 109, University of Missouri
Office phone: (573) 882-7306
Fax: (573) 882-8318

Research Interest

Bioinformatics, Systems Biology, Machine Learning and Data Mining

Research

Bioinformatics and Systems Biology Laboratory (BSBL)

The research in my group focuses on developing and applying statistical machine learning techniques to address the problems in molecular biology. Currently we are developing bioinformatics algorithms and tools for proteomics, systems biology, and genomics. We have active projects in protein structure prediction, protein interaction and docking, protein function prediction, biological sequence alignments, inference and simulation of biological networks, and machine learning ranking.

The main techniques we are using include neural networks, support vector machines, hidden Markov models, graphical models, kernel methods, clustering methods, graph algorithms, dynamic programming, differential equations, information theory, (Bayesian) statistical methods. The tools, web services, and datasets produced by our research are freely available here. Our automated tools for the prediction of protein tertiary structure, domain boundary, disorder region, and contact map were ranked among the best methods in the last Critical Assessment of Techniques for Protein Structure Prediction (CASP7), 2006.

Selected Publications